Placebo and Nocebo Phenomena from the Perspective of Evidence Based and Person Centered Medicine A
نویسنده
چکیده
Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways. Topic: Glorifi cation and vilifi cation of placebo controlled studies are the two opposite sides of the prevailing misunderstanding placebo and nocebo phenomena in medicine and pharmacology. This misunderstanding is an essential component of the pseudoscientifi c evaluation and evidence-based medicine. The using of placebo and avoidance of nocebo responses have been recommended as promising additional clinical strategies. The aim and purpose of this paper is to give a transdisciplinary and integrative overview of the placebo and nocebo from the perspective of person-centered medicine and also to provide some practical tips on how to increase placebo and decrease nocebo response in clinical practice. Conclusions: Confl icting data from clinical trials and misunderstanding of placebo and nocebo phenomena are essential components of the contamination and confusion regarding evidence-based medicine. Person-centered clinical pharmacology is partly about taking advantage of placebo and avoiding of nocebo phenomena in a clinical setting as additive eff ects to improve the eff ectiveness of the standard medication.
منابع مشابه
Futility in Complementary and Alternative Medicine: A Critical Review from an Ethical Perspective
Several definitions for medical futility has been proposed in the literature. Medical futility is defined as the condition in which an intervention, either for diagnosis, prevention, treatment, rehabilitation or other medical goals, has no benefit for the individual patient. This critical review aimed to increase the understanding of physicians and other healthcare providers on the issue of fut...
متن کاملTherapeutic Role of Placebo: Evolution of a New Paradigm in Understanding Research and Clinical Practice.
Research into interventional techniques in managing chronic spinal pain continues to be challenging, mystifying, confusing, and biased. Insight, or lack thereof, into placebo and nocebo phenomena contributes mightily to these difficulties. Unfortunately, placebo-nocebo responses are the subject of numerous controversies and challenges from not only a research perspective, but also clinical pers...
متن کاملClinical relevance of contextual factors as triggers of placebo and nocebo effects in musculoskeletal pain
Placebo and nocebo effects are embodied psycho-neurobiological responses capable of modulating pain and producing changes at different neurobiological, body at perceptual and cognitive levels. These modifications are triggered by different contextual factors (CFs) presented in the therapeutic encounter between patient and healthcare providers, such as healing rituals and signs. The CFs directly...
متن کاملExamining pornography in cyberspace from the perspective of ethics, spirituality and medicine
Background & Aims: Pornography in cyberspace is one of the emerging and multidimensional challenges in society. Each discipline offers different criteria, reasons, perspectives and solutions according to their point of view; But this multidimensional phenomenon has involved all aspects of human societies in individual and group dimensions and has left negative consequences. The aims of this stu...
متن کاملCare Integration – From “One Size Fits All” to Person Centred Care; Comment on “Achieving Integrated Care for Older People: Shuffling the Deckchairs or Making the System Watertight for the Future?”
Integrating services is a hot topic amongst health system policy-makers and healthcare managers. There is some evidence that integrated services deliver efficiencies and reduce service utilisation rates for some patient populations. In their article on Achieving Integrated Care for Older People, Gillian Harvey and her colleagues formulate some critical insights from practice and research around...
متن کامل